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HIPS probe-1

HIPS probe-1 (Compound 1) is a click chemistry reagent containing a alkyne group. HIPS probe-1 can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. HIPS probe-1 can be used as a chemical probe to specifically recognize and label aldehyde functional groups in DNA, especially abasic sites (AP sites) for DNA damage research[1].

Product Specifications

CAS Number

2490429-83-7

UNSPSC

12352005

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Smiles

C#CCN1C2=C(C=C1CN(C)N)C=CC=C2

Molecular Formula

C13H15N3

Molecular Weight

213.28

References & Citations

[1]Liu ZJ, et al. Sequencing abasic sites in DNA at single-nucleotide resolution. Nat Chem. 2019 Jul;11 (7) :629-637.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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