HIPS probe-1
HIPS probe-1 (Compound 1) is a click chemistry reagent containing a alkyne group. HIPS probe-1 can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. HIPS probe-1 can be used as a chemical probe to specifically recognize and label aldehyde functional groups in DNA, especially abasic sites (AP sites) for DNA damage research[1].
Product Specifications
CAS Number
[2490429-83-7]
UNSPSC
12352005
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Others
Smiles
C#CCN1C2=C(C=C1CN(C)N)C=CC=C2
Molecular Formula
C13H15N3
Molecular Weight
213.28
References & Citations
[1]Liu ZJ, et al. Sequencing abasic sites in DNA at single-nucleotide resolution. Nat Chem. 2019 Jul;11 (7) :629-637.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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