EIF4A-IN-3
EIF4A-IN-3 (Compound 71E) is an Eukaryotic translation initiation factor 4A (eIF4A) inhibitor. eIF4A-IN-3 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
3095005-44-7
UNSPSC
12352005
Target
ADC Payload; Eukaryotic Initiation Factor (eIF)
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O[C@]12[C@](OC3=CC(C4=NC=CO4)=CC(OC)=C32)(C5=CC=C(C=C5)OC)[C@H](C6=CC(NC(OC(C)(C)C)=O)=CC=C6)C[C@@H]1CN
Molecular Formula
C34H37N3O7
Molecular Weight
599.67
References & Citations
[1]Li B, et al. Conjugate of protein translation inhibitor and use thereof. WO2025153015A2. 2025-07-24.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
EIF4
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC880040-500 1x 500 µL
CD35 / CR1 (E11), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041081-500 1x 500 µL
CD45RO (190-2F2.5), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400304-500 1x 500 µL
CD106 / VCAM1 (B-K9), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681983-500 1x 500 µL
Carcinoembryonic Antigen (CEA) / CD66 (C66/1983R), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680612-100 1x 100 µL
MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details