EIF4A-IN-3
EIF4A-IN-3 (Compound 71E) is an Eukaryotic translation initiation factor 4A (eIF4A) inhibitor. eIF4A-IN-3 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[3095005-44-7]
UNSPSC
12352005
Target
ADC Payload; Eukaryotic Initiation Factor (eIF)
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O[C@]12[C@](OC3=CC(C4=NC=CO4)=CC(OC)=C32)(C5=CC=C(C=C5)OC)[C@H](C6=CC(NC(OC(C)(C)C)=O)=CC=C6)C[C@@H]1CN
Molecular Formula
C34H37N3O7
Molecular Weight
599.67
References & Citations
[1]Li B, et al. Conjugate of protein translation inhibitor and use thereof. WO2025153015A2. 2025-07-24.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
EIF4
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