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NOD2/TLR4 agonist-1

NOD2/TLR4 agonist-1 (Compound 2) is a NOD2/TLR4 dual agonist. NOD2/TLR4 agonist-1 lacks immunostimulatory activity and serves as an important negative control in research[1].

Product Specifications

UNSPSC

12352211

Target

NOD-like Receptor (NLR) ; Toll-like Receptor (TLR)

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

O=C(N(C1=CC=CC=C1)C(SCC(NCCCCCC(OC2=C(OC)C=C(/C=C/C(NCC(N[C@@H](C(C)C)C(N[C@@H](C(OC3CCCC3)=O)CCC(OC4CCCC4)=O)=O)=O)=O)C=C2)=O)=O)=N5)C6=C5C7=CC=CC=C7N6

Molecular Formula

C56H67N7O12S

Molecular Weight

1062.24

References & Citations

[1]Paradiso E, et al. Modulating Receptor Activity, Immune Response, and Kinetic Solubility: The Impact of Linker Chemistry in Conjugated NOD2/TLR4 Agonists. ACS Omega, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NOD2; TLR4

Curated Selection

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