308-R-C4-PEG3-C1-Boc
308-R-C4-PEG3-C1-Boc is a SGK3 ligand-linker conjugate that can be used for synthesis of PROTAC SGK3 degrader-2 (HY-176823) [1].
Product Specifications
CAS Number
[2376722-89-1]
UNSPSC
12352005
Target
SGK; Target Protein Ligand-Linker Conjugates
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Field of Research
Cancer
Smiles
O=C(OC(C)(C)C)COCCOCCOCCCCCCN(CCO1)C[C@@H]1COC2=C(C=NN3)C3=NC(C4=CC=C(C=C4)NS(=O)(C5=C(C=CC(C)=C5)F)=O)=N2
Molecular Formula
C39H53FN6O9S
Molecular Weight
800.94
References & Citations
[1]Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14 (9) :2024-2034.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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