LAG-3 Hit II

LAG-3 Hit II is a LAG-3 inhibitor with a KD of 4.32 μM. LAG-3 Hit II can be used for cancers like ovarian cancer, colon adenocarcinoma and melanoma research[1].

Product Specifications

UNSPSC

12352005

Target

LAG-3

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(NC1=C(CC(NC)=O)C=C(C2=CC=C(OC=C3)C3=C2)C=C1)[C@H]4CN(CC5=CC=CC=N5)C[C@@H]4C6=CC=CC=C6

Molecular Formula

C34H32N4O3

Molecular Weight

544.64

References & Citations

[1]Abdel-Rahman SA, et al. Discovery and Optimization of LAG-3-Targeted Small Molecules via DNA-Encoded Chemical Library (DEL) Screening for Cancer Immunotherapy. J Med Chem. 2025 Aug 20.