LAG-3 Hit II
LAG-3 Hit II is a LAG-3 inhibitor with a KD of 4.32 μM. LAG-3 Hit II can be used for cancers like ovarian cancer, colon adenocarcinoma and melanoma research[1].
Product Specifications
UNSPSC
12352005
Target
LAG-3
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(NC1=C(CC(NC)=O)C=C(C2=CC=C(OC=C3)C3=C2)C=C1)[C@H]4CN(CC5=CC=CC=N5)C[C@@H]4C6=CC=CC=C6
Molecular Formula
C34H32N4O3
Molecular Weight
544.64
References & Citations
[1]Abdel-Rahman SA, et al. Discovery and Optimization of LAG-3-Targeted Small Molecules via DNA-Encoded Chemical Library (DEL) Screening for Cancer Immunotherapy. J Med Chem. 2025 Aug 20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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