Thalidomide-amine-C11-acid

Thalidomide-amine-C11-acid is an E3 ligase ligand-linker conjugate which consists of Thalidomide 5-fluoride (HY-W087383) and a linker (HY-W105740) . Thalidomide-amine-C11-acid can be used to synthesize JQAD1 (HY-145765) [1].

Product Specifications

CAS Number

[2411665-33-1]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(CCCCCCCCCCCNC1=CC=C(C(C(N2C(C(N3)=O)CCC3=O)=O)=C1)C2=O)O

Molecular Formula

C25H33N3O6

Molecular Weight

471.55

References & Citations

[1]Durbin AD, et al. EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma. Cancer Discov. 2022 Mar 1;12 (3) :730-751.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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