Thalidomide-amine-C11-acid
Thalidomide-amine-C11-acid is an E3 ligase ligand-linker conjugate which consists of Thalidomide 5-fluoride and a linker (HY-W105740). Thalidomide-amine-C11-acid can be used to synthesize JQAD1 (HY-145765).
Product Specifications
CAS Number
2411665-33-1
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(CCCCCCCCCCCNC1=CC=C(C(C(N2C(C(N3)=O)CCC3=O)=O)=C1)C2=O)O
Molecular Formula
C25H33N3O6
Molecular Weight
471.55
References & Citations
[1]Durbin AD, et al. EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma. Cancer Discov. 2022 Mar 1;12 (3) :730-751.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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