DBCO-HS-PEG2-VA-PABC-SG3199
DBCO-HS-PEG2-VA-PABC-SG3199 is a drug-linker conjugate for ADC. DBCO-HS-PEG2-VA-PABC-SG3199 consists of a SG3199 (HY-101161) based DNA small channel crosslinker and cleavable linker. DBCO-HS-PEG2-VA-PABC-SG3199 can be used for synthesis of ADCs[1].
Product Specifications
CAS Number
[3052634-58-6]
UNSPSC
12352211
Target
DNA Alkylator/Crosslinker; Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCCC(NS(NCCOCCOCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C4)=CC=C4COC(N5C6=CC(OCCCCCOC7=C(C=C8C(N=C[C@@]9([H])N(C=C(C9)C)C8=O)=C7)OC)=C(OC)C=C6C(N%10[C@](CC(C)=C%10)([H])[C@@H]5O)=O)=O)=O)=O)=O)(=O)=O)=O
Molecular Formula
C75H86N10O18S
Molecular Weight
1447.61
References & Citations
[1]POST E, et al. Homogeneous antibody-conjugates with high payload loading. WO2024160926A1. 2024-08-08.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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