(R, S, R) -AHPC-Me-Ac
(R, S, R) -AHPC-Me-Ac is an E3 ligase ligand used in the synthesis of the PROTAC SHP2 Protein degrader-2 (HY-145703) [1].
Product Specifications
UNSPSC
12352100
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC(N[C@H](C(C)(C)C)C(N1[C@H](C[C@@H](C1)O)C(N[C@@H](C2=CC=C(C3=C(C)N=CS3)C=C2)C)=O)=O)=O
Molecular Formula
C25H34N4O4S
Molecular Weight
486.63
References & Citations
[1]Song Y, et al. Strategies Targeting Protein Tyrosine Phosphatase SHP2 for Cancer Therapy. J Med Chem. 2022 Feb 24;65 (4) :3066-3079.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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