Oxide-DFHBI-demethyl-C6-NH2
Oxide-DFHBI-demethyl-C6-NH2 is a Target Protein Ligand-Linker Conjugate that incorporates a target aptamer ligand (HY-176801) and a PROTAC linker (HY-79577), which recruits E3 ligases. Oxide-DFHBI-demethyl-C6-NH2 can be used for synthesis of RNA aptamer-based PROTAC Dth (HY-175397) [1].
Product Specifications
UNSPSC
12352100
Target
Target Protein Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1/C(N=C(C)N1CCCCCCN)=C/C2=CC(F)=C(O)C(F)=C2
Molecular Formula
C17H21F2N3O2
Molecular Weight
337.36
References & Citations
[1]Xu Y, et al. A heterobifunctional molecule recruits cereblon to an RNA scaffold and activates its PROTAC function[J]. Cell Reports Physical Science, 2022, 3 (10) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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