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LMD-902

LMD-902, a LMD-009 analog, is a CCR8 agonist with an EC50 of 15 nM. LMD-902 has a superior binging capacity depending on key residues such as PheVI:16. LMD-902 can be used for inflammation diseases like bronchial asthma and central nervous system diseases like multiple sclerosis research[1].

Product Specifications

CAS Number

521979-59-9

UNSPSC

12352100

Target

CCR

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

O=S(NCC)(C1=CC=C(C=C1C2(CCN(CC2)CC3=CC(OC4=C(OC)C=CC=C4)=CC=C3)O)OC)=O

Molecular Formula

C28H34N2O6S

Molecular Weight

526.64

References & Citations

[1]Jensen PC, et al. Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8. Mol Pharmacol. 2007 Aug;72 (2) :327-40.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CCR8

Frequently Asked Questions

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