Phenyl-glutarimide 4'-oxyacetic-amide-C5-amide-Boc
Phenyl-glutarimide 4'-oxyacetic-amide-C5-amide-Boc is an E3 ligase ligand-linker conjugate used in the synthesis of PROTAC SJ995973 (HY-145125) [1].
Product Specifications
CAS Number
[2789679-45-2]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(COC1=CC=C(C=C1)C2CCC(NC2=O)=O)NCCCCCNC(OC(C)(C)C)=O
Molecular Formula
C23H33N3O6
Molecular Weight
447.52
References & Citations
[1]Min J, et al. Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs. Angew Chem Int Ed Engl. 2021 Dec 13;60 (51) :26663-26670.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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