7-Methylol-9-methoxy-10-F-camptothecin
7-Methylol-9-methoxy-10-F-camptothecin (Compound D6-1) is a derivative of Camptothecin (HY-16560) . 7-Methylol-9-methoxy-10-F-camptothecin can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[2927485-59-2]
UNSPSC
12352005
Target
ADC Payload; Drug Derivative
Related Pathways
Antibody-drug Conjugate/ADC Related; Others
Field of Research
Cancer
Smiles
OCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(F)=C(OC)C=C51
Molecular Formula
C22H19FN2O6
Molecular Weight
426.39
References & Citations
[1]Wei W, et al. Camptothecin drug conjugate, and preparation method therefor and use thereof. WO2025087233A1. 2025-05-01.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Topo I
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