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GLP-1R agonist 34

GLP-1R agonist 34 (Compound 1) is an orally active small molecule glucagon-like peptide-1 receptor (GLP-1R) agonist. GLP-1R agonist 34 promotes insulin secretion, inhibits glucagon release, and delays gastric emptying, thereby effectively lowering blood glucose levels. GLP-1R agonist 34 is promising for research of metabolic diseases, including type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH) [1].

Product Specifications

CAS Number

[3074089-99-6]

UNSPSC

12352005

Target

GLP Receptor

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Smiles

C[C@@H]1[C@](N2C3=CC=C([C@@H]4CC(C)(OCC4)C)C=C3C=C2C(N5[C@H](C6=C(N7C(N(C8=CC=C(N(C9CC9)N=C%10)C%10=C8F)C=C7)=O)N(C%11=CC(C)=C(C(C)=C%11)F)N=C6CC5)C)=O)(C%12=NOC(N%12)=O)C1

Molecular Formula

C50H50F2N10O5

Molecular Weight

908.99

References & Citations

[1]Bin Liang, et al. GLP-1R agonist and therapeutic method thereof. US12234236B1. 2025-02-25.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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