N-Benzyl-N-demethylpronqodine A
Selected Variant
HY-176757
Size: 1 Each
N-Benzyl-N-demethylpronqodine A (Compound 16) is an inhibitor of NAD (P) H:quinine acceptor oxidoreductase 1 (NQO1) with an IC50 of 83.3 nM[1].
Product Specifications
CAS Number
1810092-90-0
UNSPSC
12352005
Target
NADPH Oxidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(C(NCC1=CC=CC=C1)=C2)C3=C(SN=C3)C2=O
Molecular Formula
C14H10N2O2S
Molecular Weight
270.31
References & Citations
[1]Blunt CE, et al., Synthesis and Intracellular Redox Cycling of Natural Quinones and Their Analogues and Identification of Indoleamine-2,3-dioxygenase (IDO) as Potential Target for Anticancer Activity. Angew Chem Int Ed Engl. 2015 Jul 20;54 (30) :8740-5. doi: 10.1002/anie.201503323. Epub 2015 Jun 10. PMID: 26096359.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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