TG-2-IN-5
TG-2-IN-5 (Compound CP4d) is a reversible TG2 inhibitor with a Ki of 1.0 μM for human TG2. TG-2-IN-5 can be used to study diseases associated with upregulation of TG2-mediated acyl transfer, such as fibrosis and cancer[1].
Product Specifications
CAS Number
[1082605-61-5]
UNSPSC
12352005
Target
Glutaminase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(C1=CN(CC2=CC=C([N+]([O-])=O)C=C2)N=N1)/C=C/C3=CC=C([N+]([O-])=O)C=C3
Molecular Formula
C18H13N5O5
Molecular Weight
379.33
References & Citations
[1]Apperley KYP, et al. Development of new scaffolds as reversible tissue transglutaminase inhibitors, with improved potency or resistance to glutathione addition. Medchemcomm. 2016 Dec 5;8 (2) :338-345.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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