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Antitumor agent-204

Antitumor agent-204 (compound 15a) is a potent antitumor agent. Antitumor agent-204 shows cytotoxicity. Antitumor agent-204 induces nitric oxide (NO) release and reactive oxygen species (ROS) generation. Antitumor agent-204 induces apoptosis and induces cell cycle arrest at G2/M phase. Antitumor agent-204 shows antitumor activity[1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis; Reactive Oxygen Species (ROS)

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Cancer

Smiles

CN1CCOC2=C3OC4=C1C=CC(CCC5=CC=C(C(OC6=CC=C(CCC3=CC=C2)C=C6)=C5)OC7=NO[N+]([O-])=C7S(=O)(C8=CC=CC=C8)=O)=C4

Molecular Formula

C39H33N3O8S

Molecular Weight

703.76

References & Citations

[1]Sun JY, et al. Discovery of hybrids of bisbibenzyl with furoxan as lysosomotropic agents for the treatment of drug-resistant non-small-cell lung cancer. Eur J Med Chem. 2025 Jun 15;296:117856.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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