ZnPc-amide-PEG3-C2-NH2
ZnPc-amide-PEG3-C2-NH2 is a photosensitizer-linker conjugate which consists of ZnPcPs (HY-176725) and a linker (HY-W040165) . ZnPc-amide-PEG3-C2-NH2 can be used to synthesize the photo-activated BRD4 degrader pZnPc-O3-JQ1 (HY-176724) [1].
Product Specifications
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(NC1=CC=C(C=C1)OC2=CC3=C(C4=NC5=[N-]6C(C7=C5C=CC=C7)=NC8=C9C=CC=CC9=C%10N=C%11C%12=C(C%13=[N-]%11[Zn+2](N8%10)6N4C3=N%13)C=CC=C%12)C=C2)CCOCCOCCOCCN
Molecular Formula
C47H38N10O5Zn
Molecular Weight
888.25
References & Citations
[1]Wang K, et al. Photo-Activated PROTACs for Targeted BRD4 Degradation and Synergistic Photodynamic Therapy in Bladder Cancer. Mol Pharm. 2025 Jun 2;22 (6) :3388-3400.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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