RD0392
RD0392 (Compound 5) is a competitive tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitor (IC50=1.3 nM) . RD0392 is promising for research of neurodegenerative diseases like Alzheimer’s[1].
Product Specifications
CAS Number
[1287651-83-5]
UNSPSC
12352100
Target
DYRK
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Neurological Disease
Smiles
OC1=CC=C(/C=C2SC(NC\2=O)=S)C=C1OCC
Molecular Formula
C12H11NO3S2
Molecular Weight
281.35
References & Citations
[1]Suzuki S, et al. Temperature vaulting: A method for screening of slow- and tight-binding inhibitors that selectively target kinases in their non-native state. Eur J Med Chem. 2025 Oct 5;295:117789.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DYRK1
Curated Selection
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