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5-HT2A receptor agonist-10

5-HT2A receptor agonist-10 (Compound (R) -I-121.HCl) is a 5-HT2A receptor agonist, with an IC50 of 2192.39 nM for h5-HT2A and h5-HT1A, respectively. 5-HT2A receptor agonist-10 can be used for the research of psychosis, mental illnesses and CNS disorders[1][2].

Product Specifications

CAS Number

3031053-17-2

UNSPSC

12352005

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

COC1=CC=C2C=NN(C2=C1)C[C@H]3CCCN3.Cl

Molecular Formula

C13H18ClN3O

Molecular Weight

267.75

References & Citations

[1]Sabnis RW, et al. Novel Indoline Derivatives as Serotonergic Psychedelic Agents for Treating Psychosis, Mental Illness and CNS Disorders. ACS Med Chem Lett. 2025 Jan 23;16 (2) :196-197. |[2]Slassi A, et al. Indazole derivatives as serotonergic agents useful for the treatment of disorders related thereto. WO2024044848A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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