5-HT2A receptor agonist-10

5-HT2A receptor agonist-10 (Compound (R) -I-121.HCl) is a 5-HT2A receptor agonist, with an IC50 of 2192.39 nM for h5-HT2A and h5-HT1A, respectively. 5-HT2A receptor agonist-10 can be used for the research of psychosis, mental illnesses and CNS disorders[1][2].

Product Specifications

CAS Number

[3031053-17-2]

UNSPSC

12352005

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

COC1=CC=C2C=NN(C2=C1)C[C@H]3CCCN3.Cl

Molecular Formula

C13H18ClN3O

Molecular Weight

267.75

References & Citations

[1]Sabnis RW, et al. Novel Indoline Derivatives as Serotonergic Psychedelic Agents for Treating Psychosis, Mental Illness and CNS Disorders. ACS Med Chem Lett. 2025 Jan 23;16 (2) :196-197. |[2]Slassi A, et al. Indazole derivatives as serotonergic agents useful for the treatment of disorders related thereto. WO2024044848A1.