NQO1 inducer 1

NQO1 inducer 1 (Compound 20) is a potent NQO1 inducer (CD=3 μM) . NQO1 inducer 1 is a promising antioxidant that can be used for the research of redox-modulating[1].

Product Specifications

UNSPSC

12352005

Target

Quinone Reductase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

NS(=O)(C1=CC=C(C=C1)N2C(C3=C(C(I)=CC(I)=C3)N=C2SCC(NC4=CC5=CC=CC=C5N=C4)=O)=O)=O

Molecular Formula

C25H17I2N5O4S2

Molecular Weight

769.37

References & Citations

[1]Soliman A M, et al. NQO1 Induction and Radiation-Based Biodistribution Study of a New Quinoline Derivative Identified in a Screen of 6, 8-Diiodoquinazolinone Sulfonamide Conjugates. European Journal of Medicinal Chemistry, 2025: 117855.