5-HT1AR agonist 3
5-HT1AR agonist 3 (Compound 77) is a 5-HT1A agonist. 5-HT1AR agonist 3 has 5-HT1A receptor agonist activity (EC50: 1.3 nM) . 5-HT1AR agonist 3 mainly exerts its effects by activating 5-HT1A receptors and can be used in the study of neuropsychiatric diseases such as anxiety, depression and sleep disorders[1].
Product Specifications
CAS Number
2410053-55-1
UNSPSC
12352100
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(C1=C2N(N=C1)C)N(CCN3CCN(CC3)C4=NSC5=C4C=CC=C5)CC2C
Molecular Formula
C21H26N6OS
Molecular Weight
410.54
References & Citations
[1]Sabnis RW. Novel Substituted Pyrazoles as 5‑HT1A Agonists for Treating Neuropsychiatric Diseases. ACS Med Chem Lett. 2025 Jun 3;16 (6) :978-979.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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