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5-HT1AR agonist 3

5-HT1AR agonist 3 (Compound 77) is a 5-HT1A agonist. 5-HT1AR agonist 3 has 5-HT1A receptor agonist activity (EC50: 1.3 nM) . 5-HT1AR agonist 3 mainly exerts its effects by activating 5-HT1A receptors and can be used in the study of neuropsychiatric diseases such as anxiety, depression and sleep disorders[1].

Product Specifications

CAS Number

2410053-55-1

UNSPSC

12352100

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

O=C(C1=C2N(N=C1)C)N(CCN3CCN(CC3)C4=NSC5=C4C=CC=C5)CC2C

Molecular Formula

C21H26N6OS

Molecular Weight

410.54

References & Citations

[1]Sabnis RW. Novel Substituted Pyrazoles as 5‑HT1A Agonists for Treating Neuropsychiatric Diseases. ACS Med Chem Lett. 2025 Jun 3;16 (6) :978-979.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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