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USP1-IN-12

USP1-IN-12 (compound 4) is a potent and orally active USP1 inhibitor with an IC50 value of 0.00366 µM. USP1-IN-12 inhibits cell clone formation[1].

Product Specifications

CAS Number

[2961035-60-7]

UNSPSC

12352005

Target

Deubiquitinase

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C1N(CC2=CC=C(C3=NC(C(F)(F)F)=CN3C(C)C)C=C2)C4=NC(C5=C(C6CC6)N=CN=C5OC)=NC=C4C17CC7

Molecular Formula

C30H28F3N7O2

Molecular Weight

575.58

References & Citations

[1]ChenZhang, et al. Azacyclic derivative and medical application thereof. WO2023143424A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

USP1

Curated Selection

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