5-Chloro-1,4-dihydro-2,3-quinoxalinedione
5-Chloro-1,4-dihydro-2,3-quinoxalinedione (Compound 72) is a weak NMDA inhibitor with an IC50 of 56.3 μM. 5-Chloro-1,4-dihydro-2,3-quinoxalinedione can be used for the research of neurological disease[1].
Product Specifications
CAS Number
[127731-60-6]
UNSPSC
12352005
Target
IGluR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C1NC2=C(C(Cl)=CC=C2)NC1=O
Molecular Formula
C8H5ClN2O2
Molecular Weight
196.59
References & Citations
[1]Leeson PD, et al. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor. J Med Chem. 1991 Apr;34 (4) :1243-52.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
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