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5-Chloro-1,4-dihydro-2,3-quinoxalinedione

5-Chloro-1,4-dihydro-2,3-quinoxalinedione (Compound 72) is a weak NMDA inhibitor with an IC50 of 56.3 μM. 5-Chloro-1,4-dihydro-2,3-quinoxalinedione can be used for the research of neurological disease[1].

Product Specifications

CAS Number

127731-60-6

UNSPSC

12352005

Target

IGluR

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

O=C1NC2=C(C(Cl)=CC=C2)NC1=O

Molecular Formula

C8H5ClN2O2

Molecular Weight

196.59

References & Citations

[1]Leeson PD, et al. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor. J Med Chem. 1991 Apr;34 (4) :1243-52.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NMDA Receptor

Frequently Asked Questions

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