H-151 Alkyne

H-151 Alkyne (Compound H-151-AL) is a selective STING (Stimulator of interferon genes) inhibitor. H-151 Alkyne is promising for research of autoimmune diseases such as systemic lupus erythematosus, scleroderma, and autoinflammatory diseases[1].

Product Specifications

CAS Number

[2244892-03-1]

UNSPSC

12352005

Target

STING

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Purity

95.08

Solubility

DMSO : 103.33 mg/mL (ultrasonic)

Smiles

O=C(NC1=CNC2=C1C=CC=C2)NC3=CC=C(C=C3)C#C

Molecular Formula

C17H13N3O

Molecular Weight

275.30

References & Citations

[1]Daniel Brewster STETSON, et al. Methods for treating autoimmune or autoinflammatory disease. WO2020180845A1. 2020-09-10.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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