H-151 Alkyne
H-151 Alkyne (Compound H-151-AL) is a selective STING (Stimulator of interferon genes) inhibitor. H-151 Alkyne is promising for research of autoimmune diseases such as systemic lupus erythematosus, scleroderma, and autoinflammatory diseases[1].
Product Specifications
CAS Number
[2244892-03-1]
UNSPSC
12352005
Target
STING
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Purity
95.08
Solubility
DMSO : 103.33 mg/mL (ultrasonic)
Smiles
O=C(NC1=CNC2=C1C=CC=C2)NC3=CC=C(C=C3)C#C
Molecular Formula
C17H13N3O
Molecular Weight
275.30
References & Citations
[1]Daniel Brewster STETSON, et al. Methods for treating autoimmune or autoinflammatory disease. WO2020180845A1. 2020-09-10.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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