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4-DTM-phenoxy-PEG3-CH2COOH

4-DTM-phenoxy-PEG4-CH2COOH (Formula 3) is a cleavable PEG-based ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

[2227345-57-3]

UNSPSC

12352005

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Cancer

Smiles

O=C(COCCOCCOCCOC1=CC=C(C=C1)N2C(C(SC3=CC=CC=C3)=C(C2=O)SC4=CC=CC=C4)=O)O

Molecular Formula

C30H29NO8S2

Molecular Weight

595.68

References & Citations

[1]Shen J K, et al. Disubstituted maleimide linker for antibody-drug coupling, preparation method and application thereof. CN108101825B. 2022-02-22.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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