Z169667518
Z169667518 is a ligand of IL-6. Z169667518 can inhibit IL-6-induced STAT3 reporter activity with an IC50 of 2.7 µM. Z169667518 can be used in the research of IL-6-related diseases[1].
Product Specifications
CAS Number
941127-19-1
UNSPSC
12352005
Target
Interleukin Related; STAT
Related Pathways
Immunology/Inflammation; JAK/STAT Signaling; Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=CC=C(C=C1)C#CC2=CC=CC=C2)NCCC3=NN=C4C=CC=CN43
Molecular Formula
C23H18N4O
Molecular Weight
366.42
References & Citations
[1]Joshi A, et al. Structure-Based Design of Small-Molecule Inhibitors of Human Interleukin-6. Molecules. 2025 Jul 10;30 (14) :2919.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-6; STAT3
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