DiABZI-Mal
DiABZI-Mal is a STING agonist with maleimide group, which can be used for the synthesis of conjugates. diABZI-Mal activates cGAS-STING pathway to induce cytokine production such as interferon-type I. diABZI-Mal promotes maturation of DC cells and efficiently induces CD8+ T immune reaction. diABZI-Mal inhibits tumor growth[1].
Product Specifications
CAS Number
2763540-24-3
UNSPSC
12352211
Target
STING
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(N)C1=CC2=C(N(C(NC(C3=CC(C)=NN3CC)=O)=N2)C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O)=NC6=C4C(OCCCN7CCN(C(CCCCCN8C(C=CC8=O)=O)=O)CC7)=CC(C(N)=O)=C6)C(OC)=C1
Molecular Formula
C52H63N15O9
Molecular Weight
1042.15
References & Citations
[1]Ji Wang, et al. Endoplasmic reticulum Golgi matrix targeting small molecule, conjugate and application thereof. Patent. CN114163420A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
