(S, R, S) -AHPC-Me-amide-C4-Br
(S, R, S) -AHPC-Me-amide-C4-Br incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. (S, R, S) -AHPC-Me-amide-C4-Br can be used to design PROTAC, such as PROTAC ERK5 degrader-1 (HY-176528) [1].
Product Specifications
CAS Number
[2521020-51-7]
UNSPSC
12352211
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
BrCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)=O)=O
Molecular Formula
C28H39BrN4O4S
Molecular Weight
607.60
References & Citations
[1]Inchul YOU, et al. Erk5 degraders and uses thereof. WO2023044482A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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