BTK degrader-1 intermediate
BTK degrader-1 intermediate (compound 5) is an intermediate for the synthesis of BTK degrader-1. BTK degrader-1 can be used as an ADC toxin to synthesize antibody-drug conjugate (ADC).
Product Specifications
CAS Number
2377643-84-8
UNSPSC
12352005
Target
Btk; Drug Intermediate
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(C1=CC=C(C(C)(C)O)C=C1F)NC2=CC(F)=CC(C3=C4C=C(C5=CC=C(CCN6CCC7(CC6)CCNCC7)C=C5)NC4=NC=N3)=C2C
Molecular Formula
C40H44F2N6O2
Molecular Weight
678.81
References & Citations
[1]Zhang A, et al. Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton's Tyrosine Kinase (BTK) Degrader CD79b Targeted Antibody-Drug Conjugates. Bioconjug Chem. 2024 Feb 21;35 (2) :140-146.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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