PLC-β-IN-1
PLC-β-IN-1 (Compound 8a) is a PLCβ inhibitor. PLC-β-IN-1 exerts anti-airway contraction activity by inhibiting PLCβ and its downstream signaling pathways, and can enhance the airway relaxation effect of β-agonists. PLC-β-IN-1 can be used in the study of asthma[1].
Product Specifications
UNSPSC
12352211
Target
Phospholipase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O=C(/C=C/CCCCC)/C=C/C1=CC(C(F)(F)F)=C(O)C(CO)=C1
Molecular Formula
C18H21F3O3
Molecular Weight
342.35
References & Citations
[1]Luković E, et al. Design and Evaluation of Novel Ginger 6-Shogaol-Inspired Phospholipase C Inhibitors to Enhance β-Agonist-Induced Relaxation in Human Airway Smooth Muscle. J Med Chem. 2025 Jun 26;68 (12) :12626-12640.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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