Trimethoprim-PEG3-amine (TFA)

Trimethoprim-PEG3-amine TFA is a small molecule probe. Trimethoprim-PEG3-amine TFA allows for binding to protein targets. Trimethoprim-PEG3-amine TFA modified by an azide group serves as a click chemistry reagent, and it can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Alkyne groups like Ethinylestradiol (HY-B0216) [1].

Product Specifications

CAS Number

[2108550-88-3]

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Others

Smiles

COC1=C(C(OC)=CC(CC2=CC(N)=NC(N)=N2)=C1)OCC(NCCOCCOCCOCCN)=O.FC(C(O)=O)(F)F.FC(C(O)=O)(F)F.FC(C(O)=O)(F)F

Molecular Formula

C29H39F9N6O13

Molecular Weight

850.64

References & Citations

[1]Wang P, et al. Using the yeast three-hybrid system for the identification of small molecule-protein interactions with the example of ethinylestradiol. Biol Chem. 2022 Feb 28;403 (4) :421-431.