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FO-32

FO-32 is an ionizable cationic lipid with a pKa of 6.46 and can be used to generate lipid nanoparticles (LNPs) to deliver mRNA in vivo. FO-32 can efficiently deliver mRNA to ferret lungs. FO-32 can be studied in research on optimizing drug delivery[1].

Product Specifications

UNSPSC

12352211

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

O=C(N(C(CCCC(OCCC#CCCCCCC)=O)(C(NCCCC)=O)CCCC(OCCC#CCCCCCC)=O)CCCN(C)C)CCCCC(OC(CCCCCCCC)CCCCCCCC)=O

Molecular Formula

C62H111N3O8

Molecular Weight

1026.56

References & Citations

[1]Witten, J., et al., (2024) . Artificial intelligence-guided design of lipid nanoparticles for pulmonary gene therapy. Nature biotechnology.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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