Elafibranor sulfoxide
Elafibranor (GFT505) sulfoxide is a sulfoxide metabolite of Elafibranor (HY-16737) . Elafibranor is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis[1].
Product Specifications
UNSPSC
12352005
Target
Drug Metabolite; PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease; Inflammation/Immunology
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(OC1=C(C=C(C=C1C)/C=C/C(C2=CC=C(C=C2)S(C)=O)=O)C)(C(O)=O)C
Molecular Formula
C22H24O5S
Molecular Weight
400.49
References & Citations
[1]Ratziu V, et al. Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-α and -δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening. Gastroenterology. 2016 May;150 (5) :1147-1159.e5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1104800-01 1 mg (E-Coli)
Recombinant Cryptococcus neoformans var. neoformans serotype D Probable O-acetyltransferase CAS1 (CAS1), partial
Ask
View Details 
MBS1104800-02 1 mg (Yeast)
Recombinant Cryptococcus neoformans var. neoformans serotype D Probable O-acetyltransferase CAS1 (CAS1), partial
Ask
View Details ![Human Monoclonal Cyr61/CCN1 Antibody (Roche patent anti-CCN1) [Alexa Fluor 532]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
NBP3-27957AF532 0.1 mL
Human Monoclonal Cyr61/CCN1 Antibody (Roche patent anti-CCN1) [Alexa Fluor 532]
Ask
View Details 