Deoxy-thalidomide-alkyne-hexanoic acid
Deoxy-thalidomide-alkyne-hexanoic acid is a E3 ligase ligand-linker conjugate that can be used for synthesis of PROTAC degrader SD-91 (HY-150251) [1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(O)CCCCCC#CC1=C2C(C(N(C3C(NCCC3)=O)C2)=O)=CC=C1
Molecular Formula
C21H24N2O4
Molecular Weight
368.43
References & Citations
[1]Zhou H, et al. SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression. ACS Med Chem Lett. 2021 May 10;12 (6) :996-1004.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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