NOP antagonist 1
NOP antagonist 1 (Compound (-) -31) is a nociceptin opioid peptide (NOP) antagonist with a Kb of 8.65 nM. NOP antagonist 1 can be used for neuropsychiatric disorders research[1].
Product Specifications
CAS Number
1283095-64-6
UNSPSC
12352005
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
FC1=CC2=C(C3(OCC2)CCN(CC3)C[C@@H](C(N)=O)CC4=C(C=CC=C4)F)S1
Molecular Formula
C21H24F2N2O2S
Molecular Weight
406.49
References & Citations
[1]Pedregal C, et al. Development of LC-MS/MS-based receptor occupancy tracers and positron emission tomography radioligands for the nociceptin/orphanin FQ (NOP) receptor. J Med Chem. 2012 Jun 14;55 (11) :4955-67.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NOP Receptor/ORL1
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