Adenosine receptor agonist 2
Adenosine receptor agonist 2 (Compound 10) is an adenosine A2B receptor (A2BR) agonist with an EC50 of 0.38 nM. Adenosine receptor agonist 2 significantly inhibits the accumulation of cAMP and calcium. Adenosine receptor agonist 2 can be used for cardioprotection research[1].
Product Specifications
CAS Number
2789709-35-7
UNSPSC
12352005
Target
Adenosine Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C3=NC=NC(NCCCCCCN(N=N4)C=C4C(C=C5)=CC=C5C6=C(C7=CC(C(F)(F)F)=CC=C7)C(C(C8=CC=CC=C8)=O)=C(N)S6)=C3N=C2)O1
Molecular Formula
C42H40F3N9O5S
Molecular Weight
839.88
References & Citations
[1]Awalt JK, et al. Examining the Role of the Linker in Bitopic N6-Substituted Adenosine Derivatives Acting as Biased Adenosine A1 Receptor Agonists. J Med Chem. 2022 Jul 14;65 (13) :9076-9095.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A2B receptor (A2BR)
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