DMDHP
DMDHP is a cationic lipid with a polar head group containing a dihydroxy group. DMDHP exhibits superior transfection efficiency and lower toxicity at high DNA doses in mouse intrapulmonary transfection model. DMDHP is commonly used for gene delivery[1].
Product Specifications
CAS Number
[189743-89-3]
Product Name Alternative
(±) -Dimyristoyl-2,3-dimethylhydroxypropylamine
UNSPSC
12352211
Target
Liposome
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Smiles
O=C(CCCCCCCCCCCCC)OCC(C[N+](CCO)(CCO)C)OC(CCCCCCCCCCCCC)=O.[I-]
Molecular Formula
C36H72INO6
Molecular Weight
741.86
References & Citations
[1]Bennett MJ, et al. Cationic lipid-mediated gene delivery to murine lung: correlation of lipid hydration with in vivo transfection activity. J Med Chem. 1997 Dec 5;40 (25) :4069-78.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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