NBM-T-BMX-OS01
NBM-T-BMX-OS01 is an Osthole derivative. NBM-T-BMX-OS01 inhibits the phosphorylation of VEGFR2, FAK, Akt and ERK. NBM-T-BMX-OS01 has anti-angiogenic activity. NBM-T-BMX-OS01 has anti-cancer activity against colorectal cancer[1].
Product Specifications
CAS Number
1246952-34-0
Product Name Alternative
BMX
UNSPSC
12352005
Target
Akt; FAK; PERK; VEGFR
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
COC(C=C1)=CC=C1COC2=C(C(OC)=CC=C2/C=C/C(NO)=O)C/C=C(C)\C
Molecular Formula
C23H27NO5
Molecular Weight
397.46
References & Citations
[1]Yang HY, et al. Anti-cancer activity of an osthole derivative, NBM-T-BMX-OS01: targeting vascular endothelial growth factor receptor signaling and angiogenesis. PLoS One. 2013 Nov 27;8 (11) :e81592.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1
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