GW273297X
GW273297X is a CYP27A1 inhibitor. GW273297X reduces 27HC concentration in E0771 tumors in APOE3 mice. GW273297X can be used in breast cancer research[1].
Product Specifications
CAS Number
[1713317-28-2]
Product Name Alternative
G297X
UNSPSC
12352211
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
C[C@@]12[C@]3([H])[C@]([C@@H](C[C@]1([H])CC(OC)(CC2)OC)O)([H])[C@@]4([H])[C@](CC3)([C@H](CC4)[C@H](C)CCCCC#C)C
Molecular Formula
C29H48O3
Molecular Weight
444.69
References & Citations
[1]Donald P. Mcdonnell, et al. Use of cyp27a1 inhibitors, statin, or lxr antagonists alone or in combination with conventional therapy for the treatment of breast cancer. WO2015065505A1. Duke University. 2014-01-03.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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