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GW273297X

GW273297X is a CYP27A1 inhibitor. GW273297X reduces 27HC concentration in E0771 tumors in APOE3 mice. GW273297X can be used in breast cancer research[1].

Product Specifications

CAS Number

[1713317-28-2]

Product Name Alternative

G297X

UNSPSC

12352211

Target

Cytochrome P450

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

C[C@@]12[C@]3([H])[C@]([C@@H](C[C@]1([H])CC(OC)(CC2)OC)O)([H])[C@@]4([H])[C@](CC3)([C@H](CC4)[C@H](C)CCCCC#C)C

Molecular Formula

C29H48O3

Molecular Weight

444.69

References & Citations

[1]Donald P. Mcdonnell, et al. Use of cyp27a1 inhibitors, statin, or lxr antagonists alone or in combination with conventional therapy for the treatment of breast cancer. WO2015065505A1. Duke University. 2014-01-03.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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