E3 Ligase Ligand-linker Conjugate 193
E3 Ligase Ligand-linker Conjugate 193 is an E3 ligase ligand-linker conjugate that incorporates the VHL Ligase Ligand and linker (HY-176491). E3 Ligase Ligand-linker Conjugate 193 can be used for synthesis of PROTAC pan-KRAS degrader-1 (HY-176489).
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
OCC1(CC1)CN2CCC(OC3=NC=C(C4=CN([C@@H](C(C)C)C(N5C[C@H](O)C[C@H]5C(N[C@@H](C)C6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)N=N4)N=C3)CC2
Molecular Formula
C38H49N9O5S
Molecular Weight
743.92
References & Citations
[1]Xu Renqi, et al. Pan-kras protein targeted degrader compound and use thereof. Patent. WO2025039676.2025-02-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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