E3 Ligase Ligand-linker Conjugate 193

E3 Ligase Ligand-linker Conjugate 193 is an E3 ligase ligand-linker conjugate that incorporates the VHL Ligase Ligand (HY-170353) and linker (HY-176491) . E3 Ligase Ligand-linker Conjugate 193 can be used for synthesis of PROTAC pan-KRAS degrader-1 (HY-176489) [1].

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

OCC1(CC1)CN2CCC(OC3=NC=C(C4=CN([C@@H](C(C)C)C(N5C[C@H](O)C[C@H]5C(N[C@@H](C)C6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)N=N4)N=C3)CC2

Molecular Formula

C38H49N9O5S

Molecular Weight

743.92

References & Citations

[1]Xu Renqi, et al. Pan-kras protein targeted degrader compound and use thereof. Patent. WO2025039676.2025-02-27.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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