Alkyne-pyrazine-O-piperidine- (1-methylcyclopropyl) methanol
Alkyne-pyrazine-O-piperidine- (1-methylcyclopropyl) methanol is a PROTAC linker that can be used in the synthesis of PROTACs, such as PROTAC pan-KRAS degrader-1 (HY-176489) [1].
Product Specifications
UNSPSC
12352005
Target
PROTAC Linkers
Related Pathways
PROTAC
Smiles
OCC1(CC1)CN2CCC(OC3=NC=C(C#C)N=C3)CC2
Molecular Formula
C16H21N3O2
Molecular Weight
287.36
References & Citations
[1]Xu Renqi, et al. Pan-kras protein targeted degrader compound and use thereof. Patent. WO2025039676. 2025-02-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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