Pan-KRAS ligand 3
Pan-KRAS ligand 3 is a pan-KRAS inhibitor. Pan-KRAS ligand 3 can be used for synthesis of PROTAC pan-KRAS degrader-1 (HY-176489) [1].
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; PROTAC
Field of Research
Cancer
Smiles
FC(C=C1)=C(CC)C(C1=CC(O)=C2)=C2C3=NC=C4C(N=C(Cl)N=C4N5CCC[C@@](C)(O)C5)=C3F
Molecular Formula
C25H23ClF2N4O2
Molecular Weight
484.93
References & Citations
[1]Xu Renqi, et al. Pan-kras protein targeted degrader compound and use thereof. Patent. WO2025039676. 2025-02-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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