CYP11B2-IN-3
CYP11B2-IN-3 (compound 32) is an orally active and selective CYP11B2 inhibitor with IC50 values of 12.92 nM and 2341 nM for CYP11B2 and CYP11B1, respectively. CYP11B2-IN-3 can be used for study of hypertension[1].
Product Specifications
CAS Number
[3072732-90-9]
UNSPSC
12352005
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
O=C(CC)N[C@H](CCC1)C2=C1C(C3=CC(Cl)=C(C4=CC=NN4C)C=C3)=CN=C2
Molecular Formula
C22H23ClN4O
Molecular Weight
394.90
References & Citations
[1]Guangyuan Shen, et al. Development of Highly Selective Aldosterone Synthase Inhibitors. ACS Medicinal Chemistry LettersVol 16/Issue 6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP11
Curated Selection
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