PAB- (PEG4-Me) -Cit-Val-PEG2-amide-C2-MC
PAB- (PEG4-Me) -Cit-Val-PEG2-amide-C2-MC is an ADC linker that can be combined with the TLR7/8 agonist for the synthesis of a linker-payload conjugate[1].
Product Specifications
UNSPSC
12352203
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Smiles
OCC1=C(C(NCCOCCOCCOCCOC)=O)C=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCNC(CCN2C(C=CC2=O)=O)=O)=O)=O)=O)C=C1
Molecular Formula
C42H66N8O15
Molecular Weight
923.02
References & Citations
[1]Yamazoe S, et al. Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity. J Med Chem. 2025 Jun 12;68 (11) :11322-11339.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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