PAB- (PEG4-Me) -Cit-Val-PEG2-amide-C2-MC

PAB- (PEG4-Me) -Cit-Val-PEG2-amide-C2-MC is an ADC linker that can be combined with the TLR7/8 agonist (HY-170770) for the synthesis of a linker-payload conjugate[1].

Product Specifications

UNSPSC

12352203

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Cancer

Smiles

OCC1=C(C(NCCOCCOCCOCCOC)=O)C=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCNC(CCN2C(C=CC2=O)=O)=O)=O)=O)=O)C=C1

Molecular Formula

C42H66N8O15

Molecular Weight

923.02

References & Citations

[1]Yamazoe S, et al. Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity. J Med Chem. 2025 Jun 12;68 (11) :11322-11339.