TAF1 ligand 1
TAF1 ligand 1 is a TAF1 ligand. TAF1 ligand 1 can be used as a Ligands for Target Protein for PROTAC synthesis, such as ZS3-046 (HY-176457) [1].
Product Specifications
CAS Number
[1926986-25-5]
UNSPSC
12352005
Target
Epigenetic Reader Domain; Ligands for Target Protein for PROTAC
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1C2=C(C=CN2)C(C3=CC(C(N4CCOCC4)=O)=CC5=C3N=CN5)=CN1CCC=C
Molecular Formula
C23H23N5O3
Molecular Weight
417.46
References & Citations
[1]Chen L, et al. PROTAC-Mediated Degradation of TAF1 Induces Apoptosis in AML Cells and Inhibits Tumor Growth In Vivo. Mol Cancer Ther. 2025 May 16:OF1-OF10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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