Nek2/Hec1-IN-3
Nek2/Hec1-IN-3 (Compound 11-28) is a Hec1/Nek2 interaction inhibitor. Nek2/Hec1-IN-3 disrupts Nek2/Hec1 binding and can be used for research of neoplastic diseases[1].
Product Specifications
CAS Number
[457940-87-3]
UNSPSC
12352005
Target
NEKs
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.05
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=NC=CC=C1)NC2=NC(C3=CC=C(C)C=C3)=CS2
Molecular Formula
C16H13N3OS
Molecular Weight
295.36
References & Citations
[1]Yu-Ling Huang, et al. Improved modulators of hec1 activity and methods therefor. Patent. WO2013082324A1
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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